A coumarin with diverse biological activities; inhibits LPS-induced nitric oxide production in mouse peritoneal macrophages (IC50 = 20 µM); completely inhibits collagen-induced aggregation of isolated rabbit platelets at 100 µg/ml; inhibits BChE (IC50 = 12.96 µg/ml); reduces triacylglycerol levels and expression of the genes encoding SREBP-1c

Pteryxin – 25 mg

Brand:
Cayman
CAS:
13161-75-6
Storage:
-20
UN-No:
Non-Hazardous - /

Pteryxin is a coumarin that has been found in A. furcijuga and has diverse biological activities.{46928,46927,46929,46930} It inhibits LPS-induced nitric oxide production in mouse peritoneal macrophages (IC50 = 20 µM).{46928} Pteryxin (100 µg/ml) completely inhibits collagen-induced aggregation of isolated rabbit platelets.{46927} It inhibits butyrylcholinesterase (BChE; IC50 = 12.96 µg/ml).{46929} Pteryxin reduces triacylglycerol levels and expression of the genes encoding sterol regulatory element binding protein 1c (SREBP-1c), fatty acid synthase (FASN), and acetyl-coenzyme A carboxylase 1 (ACC1) in 3T3-L1 adipocytes and HepG2 cells.{46930}  

 

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SKU: 30320 - 25 mg Category:

Description

A coumarin with diverse biological activities; inhibits LPS-induced nitric oxide production in mouse peritoneal macrophages (IC50 = 20 µM); completely inhibits collagen-induced aggregation of isolated rabbit platelets at 100 µg/ml; inhibits BChE (IC50 = 12.96 µg/ml); reduces triacylglycerol levels and expression of the genes encoding SREBP-1c, FASN, and ACC1 in 3T3-L1 adipocytes and HepG2 cells

Formal name: (2Z)-2-methyl-2-butenoic acid, (9R,10R)-9-(acetyloxy)-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b′]dipyran-10-yl ester

Synonyms:  (+)-Pteryxin|Pterixin|Pteryxine

Molecular weight: 386.4

CAS: 13161-75-6

Purity: ≥98%

Formulation: A crystalline solid

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