A naturally-occurring dimethyl ether analog of resveratrol; acts as a powerful antioxidant

Pterostilbene – 100 mg

Brand:
Cayman
CAS:
537-42-8
Storage:
-20
UN-No:
De Minimis - 3077 / 9

Pterostilbene is a naturally-occurring dimethyl ether analog of resveratrol that is abundant in blueberries. Like resveratrol, pterostilbene acts as a powerful antioxidant, suppresses the synthesis of prostaglandin E2 from lipopolysaccharide-stimulated human peripheral blood mononuclear cells (IC50 = 1.0 μM for pterostilbene, 3.2 μM for resveratrol), and inhibits cell proliferation (IC50 = ~60 μM for both compounds).{17408,17409,17410} Pterostilbene blocks the activation of ERK1/2, p38 MAPK, and PI3K/Akt signaling pathways, reducing NF-κB and AP-1 transcriptional activation.{17411,17412,17413} Through these actions, pterostilbene evokes effects that prevent cancer, inflammation, and diabetes.  

 

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SKU: 13000 - 100 mg Category:

Description

A naturally-occurring dimethyl ether analog of resveratrol; acts as a powerful antioxidant, suppresses the synthesis of PGE2 from LPS-stimulated human peripheral blood mononuclear cells (IC50 = 1.0 μM), and inhibits cell proliferation (IC50 = ~60 μM); evokes effects that prevent cancer, inflammation, and diabetes

Formal name: 4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl)-phenol

Synonyms:  trans-3,5-Dimethoxy-4′-Hydroxystilbene|3′,5′-Dimethoxy-4-Stilbenol

Molecular weight: 256.3

CAS: 537-42-8

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Stilbenes||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Cancer|Cell Signaling|ERK/MAPK Signaling||Research Area|Cancer|Cell Signaling|p38 MAPK Signaling||Research Area|Cancer|Cell Signaling|PI3K/Akt/mTOR Signaling||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Prostaglandins||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity

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