A synthetic analog of natural PtdIns containing C8:0 fatty acids at the sn-1 and sn-2 positions; contains the same inositol and DAG stereochemistry as the natural compound

PtdIns-(4)-P1 (1,2-dioctanoyl) (ammonium salt) – 500 µg

Brand:
Cayman
CAS:
1246303-11-6
Storage:
-20
UN-No:
Non-Hazardous - /

The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals.{4096,8344} PtdIns-(4)-P1 (1,2-dioctanoyl) is a synthetic analog of natural phosphatidylinositol (PtdIns) featuring C8:0 fatty acids at the sn-1 and sn-2 positions. The compound contains the same inositol and diacylglycerol (DAG) stereochemistry as the natural compound. PtdIns-(4)-P1 can be phosphorylated to di- (PtdIns-P2; PIP2) and triphosphates (PtdIns-P3; PIP3). Hydrolysis of PtdIns-(4,5)-P2 by phosphoinositide (PI)-specific phospholipase C generates inositol triphosphate (IP3) and DAG which are key second messengers in an intricate biochemical signal transduction cascade.  

 

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SKU: 10007711 - 500 µg Category:

Description

A synthetic analog of natural PtdIns containing C8:0 fatty acids at the sn-1 and sn-2 positions; contains the same inositol and DAG stereochemistry as the natural compound

Formal name: 1-(1,2-dioctanoylphosphatidyl)inositol-4-phosphate, diammonium salt

Synonyms:  DOPI-4-P1|Phosphatidylinositol-4-phosphate C-8

Molecular weight: 700.7

CAS: 1246303-11-6

Purity: ≥97%

Formulation: A lyophilized powder

Product Type|Biochemicals|Lipids|Glycerophospholipids||Research Area|Cell Biology|Inositol Phosphates||Research Area|Lipid Biochemistry|Glycerophospholipids

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