PtdIns-(1,2-dioctanoyl) (sodium salt) – 100 µg

Brand:
Cayman
CAS:
899827-36-2
Storage:
-20
UN-No:
Non-Hazardous - /

The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals.{4096,8344} PtdIns-(1,2-dioctanoyl) is a synthetic analog of natural phosphatidylinositol (PtdIns) containing C8:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and diacyl glycerol (DAG) stereochemistry as that of the natural compound. The short fatty acid chains of this analog, compared to naturally-occurring PtdIns, gives it different physical properties including high solubility in aqueous media. PtdIns are phosphorylated to mono- (PtdIns-P; PIP), di- (PtdIns-P2; PIP2), and triphosphates (PtdIns-P3; PIP3). Hydrolysis of PtdIns-(4,5)-P2 by phosphoinositide (PI)-specific phospholipase C generates inositol triphosphate (IP3) and DAG which are key second messengers in an intricate biochemical signal transduction cascade.  

 

Available on backorder

SKU: 10008099 - 100 µg Category:

Description

A synthetic analog of natural PtdIns containing C8:0 fatty acids at the sn-1 and sn-2 positions; contains the same inositol and DAG stereochemistry as the natural compound


Formal name: 1-(1,2-dioctanoylphosphatidyl)inositol, monosodium salt

Synonyms:  DOPI|Phosphatidylinositol C-8

Molecular weight: 608.6

CAS: 899827-36-2

Purity: ≥98%

Formulation: A lyophilized powder


Product Type|Biochemicals|Lipids|Glycerophospholipids||Research Area|Cell Biology|Inositol Phosphates||Research Area|Lipid Biochemistry|Glycerophospholipids