A phosphoramidate prodrug of PSI-7851

PSI-7977 – 5 mg

Brand:
Cayman
CAS:
1190307-88-0
Storage:
-20
UN-No:
Non-Hazardous - /

PSI-7977 is a phosphoramidate prodrug of PSI-7851, a nucleoside analog that, when phosphorylated, inhibits the RNA-dependent RNA polymerase of hepatitis C virus (EC50 = 92 nM).{25066,25069,25067} PSI-7977 is effective in vitro and in vivo.{25069,25065,25068}  

 

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Description

A phosphoramidate prodrug of PSI-7851, a nucleoside analog that, when phosphorylated, inhibits the RNA-dependent RNA polymerase of hepatitis C virus (EC50 = 92 nM); effective in vitro and in vivo

Formal name: N-[[P(S),2’R]-2′-deoxy-2′-fluoro-2′-methyl-P-phenyl-5′-uridylyl]-L-alanine, 1-methylethyl ester

Synonyms:  GI-7977|Sofosbuvir

Molecular weight: 529.5

CAS: 1190307-88-0

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antivirals|DNA & RNA Polymerase Inhibitors||Product Type|Biochemicals|Small Molecule Inhibitors|Nucleic Acid Turnover/Signaling||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Viral Diseases|Hepatitis

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