A secondary metabolite produced by fungi; inhibits IgE production by mouse B cells in culture (IC50 = 3.6 μM) and dose-dependently (0.4-25 μg/ml) stimulates neuritogenic activity in rat pheochromocytoma PC12 cells; demonstrates nematicidal activity at 300 μg/ml

Pseurotin A – 1 mg

Brand:
Cayman
CAS:
58523-30-1
Storage:
-20
UN-No:
Non-Hazardous - /

Pseurotin A is a secondary metabolite produced by Aspergillus and other fungi.{22508} Its expression is induced in response to hypoxia.{22509} Pseurotin A has been shown to inhibit IgE production by mouse B cells in culture (IC50 = 3.6 μM) and dose-dependently (0.4-25 μg/ml) stimulate neuritogenic activity in rat pheochromocytoma PC12 cells.{22505,22507} It also demonstrates nematicidal activity at 300 μg/ml.{22504}  

 

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Description

A secondary metabolite produced by fungi; inhibits IgE production by mouse B cells in culture (IC50 = 3.6 μM) and dose-dependently (0.4-25 μg/ml) stimulates neuritogenic activity in rat pheochromocytoma PC12 cells; demonstrates nematicidal activity at 300 μg/ml

Formal name: (5S)-8S-benzoyl-2-[1S,2S-dihydroxy-3Z-hexen-1-yl]-9R-hydroxy-8-methoxy-3-methyl-1-oxa-7-azaspiro[4.4]non-2-ene-4,6-dione

Synonyms:  NSC 348694

Molecular weight: 431.4

CAS: 58523-30-1

Purity: ≥98%

Formulation: A powder

Product Type|Biochemicals|Natural Products|Microbial Metabolites||Research Area|Immunology & Inflammation|Adaptive Immunity||Research Area|Infectious Disease|Parasitic Diseases

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