A diterpene acid isolated from the bark of P. kaempferi

Pseudolaric Acid B – 500 µg

Brand:
Cayman
CAS:
82508-31-4
Storage:
-20
UN-No:
De Minimis - 2811 / 6.1

Pseudolaric acid B (PAB) is a diterpene acid isolated from the bark of P. kaempferi, a traditional Chinese medicinal plant. It has reported antifungal activities, consistent with its traditional use in the treatment of dermatological fungal infections.{17624} Moreover, PAB has diverse effects that are relevant to cancer therapy, including inducing apoptosis of cancer cells (IC50 = ~1 μM), preventing angiogenesis, and inhibiting tumor growth in vivo.{17625,17627,17626}  

 

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Description

A diterpene acid isolated from the bark of P. kaempferi, a traditional Chinese medicinal plant; has antifungal activities and diverse effects that are relevant to cancer therapy

Formal name: (3R,4S,4aS,9aR)-4a-(acetyloxy)-3-[(1E,3E)-4-carboxy-1,3-pentadien-1-yl]-3,4,4a,5,6,9-hexahydro-3-methyl-1-oxo-1H-4,9a-ethanocyclohepta[c]pyran-7-carboxylic acid, 7-methyl ester

Synonyms:  NSC 615488|PAB

Molecular weight: 432.5

CAS: 82508-31-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antifungals||Product Type|Biochemicals|Natural Products|Terpenes||Research Area|Cancer|Angiogenesis||Research Area|Cancer|Cell Death|Apoptosis

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