A CB1 and CB2 agonist with EC50 values of 56 and 14 nM

PSB-SB1202 – 5 mg

Brand:
Cayman
CAS:
1399049-60-5
Storage:
-20
UN-No:
Non-Hazardous - /

PSB-SB1202 is a benzylcoumarin compound that acts as an agonist at the major cannabinoid (CB) receptors, with EC50 values of 56 and 14 nM at CB1 and CB2, respectively.{26899} It is highly selective for the CB1 and CB2 receptors (Kis = 32 and 49 nM, respectively), having minimal activity at GPR55 (IC50 = 6.4 µM), a receptor that binds CBs and lysophosphatidylinositol.{26900}  

 

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Description

A CB1 and CB2 agonist with EC50 values of 56 and 14 nM, respectively; selective for the CB1 and CB2 receptors (Kis = 32 and 49 nM, respectively) over GPR55 (IC50 = 6.4 µM),

Formal name: 5-methoxy-3-[(2-methoxyphenyl)methyl]-7-pentyl-2H-1-benzopyran-2-one

Synonyms: 

Molecular weight: 366.5

CAS: 1399049-60-5

Purity: ≥98%

Formulation: A crystalline solid

Application||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Neuroscience|Cannabinoid Research|CB1 & CB2 Receptors

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