A prodrug from of ulifloxacin; increases survival in various mouse models of systemic bacterial infection (ED50s = 0.35-23 mg/kg); increases survival in a mouse model of K. pneumoniae-induced respiratory tract infection (ED50 = 0.981 mg/kg)

Prulifloxacin – 1 g

Brand:
Cayman
CAS:
123447-62-1
Storage:
-20
UN-No:
Non-Hazardous - /

Prulifloxacin is a prodrug form of the fluoroquinolone antibiotic ulifloxacin.{52851} In vivo, prulifloxacin increases survival in mouse models of systemic S. aureus, S. pyogenes, S. pneumoniae, E. coli, K. pneumoniae, S. marcescens, or P. aeruginosa infection (ED50s = 0.35-23 mg/kg). It also increases survival in a mouse model of K. pneumoniae-induced respiratory tract infection (ED50 = 0.981 mg/kg).  

 

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SKU: 31624 - 1 g Category:

Description

A prodrug from of ulifloxacin; increases survival in various mouse models of systemic bacterial infection (ED50s = 0.35-23 mg/kg); increases survival in a mouse model of K. pneumoniae-induced respiratory tract infection (ED50 = 0.981 mg/kg)

Formal name: 6-fluoro-1-methyl-7-[4-[(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl]-1-piperazinyl]-4-oxo-1H,4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid

Synonyms:  NM441

Molecular weight: 461.5

CAS: 123447-62-1

Purity: ≥98%

Formulation: A crystalline solid

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