A methylxanthine derivative that has bronchodilatory

Proxyphylline – 5 g

Brand:
Cayman
CAS:
603-00-9
Storage:
-20
UN-No:
Non-Hazardous - /

Proxyphylline is a methylxanthine derivative that has bronchodilatory actions.{32897} It has also been reported to have vasodilatory and cardiac stimulatory effects.{32898} Proxyphylline selectively antagonizes A1 adenosine receptors (Ki = 82 nM for bovine brain) versus A2 adenosine receptors (Ki = 850 µM for platelets).{29142} Proxyphylline has been mixed with Melilotus extract to generate a theo-esberiven product, which can have cardiovascular and anti-allodynia effects in mammals.{32898,32896}  

 

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Description

A methylxanthine derivative that has bronchodilatory, vasodilatory, and cardiac stimulatory effects; selectively antagonizes A1 adenosine receptors (Ki = 82 nM for bovine brain)

Formal name: 3,7-dihydro-7-(2-hydroxypropyl)-1,3-dimethyl-1H-purine-2,6-dione

Synonyms:  NSC 163343

Molecular weight: 238.2

CAS: 603-00-9

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Cardiovascular System|Vasculature|Vasodilation||Research Area|Immunology & Inflammation|Allergy

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