PGG2 is the first intermediate in the COX pathway which is stable enough to be isolated and characterized.{499} It is the C-15 hydroperoxide of PGH2. Under normal conditions

Prostaglandin G2 – 25 µg

Brand:
Cayman
CAS:
51982-36-6
Storage:
-80
UN-No:
De Minimis - 1090 / 3

Prostaglandin G2 (PGG2) is the first intermediate in the COX pathway which is stable enough to be isolated and characterized.{499} It is the C-15 hydroperoxide of PGH2. Under normal conditions, PGG2 is quickly metabolized by the peroxidase activity intrinsic to both COX-1 and -2 to give PGH2, which serves as the key precursor to the 2-series PGs and thromboxanes.{499,759}  

 

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Description

PGG2 is the first intermediate in the COX pathway which is stable enough to be isolated and characterized.{499} It is the C-15 hydroperoxide of PGH2. Under normal conditions, PGG2 is quickly metabolized by the peroxidase activity intrinsic to both COX-1 and -2 to give PGH2, which serves as the key precursor to the 2-series PGs and thromboxanes.{499,759}

Formal name: 9α,11α-epidioxy-15S-hydroperoxy-prosta-5Z,13E-dien-1-oic acid

Synonyms:  PGG2

Molecular weight: 368.5

CAS: 51982-36-6

Purity: ≥95%

Formulation: A solution in acetone

Product Type|Biochemicals|Lipids|Prostaglandins||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway

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