PGF2α-OH is an analog of PGF2α in which the C-1 carboxyl group has been reduced to a primary alcohol. Biological studies on rat uterus show it to be a weak agonist.{7477} The compound is reported to retain ocular hypotensive properties

Prostaglandin F2α Alcohol – 5 mg

Brand:
Cayman
CAS:
13261-27-3
Storage:
-20
UN-No:
De Minimis - 1231 / 3

Prostaglandin F2α alcohol (PGF2α-OH) is an analog of PGF2α in which the C-1 carboxyl group has been reduced to a primary alcohol. Biological studies on rat uterus show it to be a weak agonist.{7477} The compound is reported to retain ocular hypotensive properties,{7418} but the nature of the receptors which mediate these effects is disputed.{9585}  

 

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Description

PGF2α-OH is an analog of PGF2α in which the C-1 carboxyl group has been reduced to a primary alcohol. Biological studies on rat uterus show it to be a weak agonist.{7477} The compound is reported to retain ocular hypotensive properties,{7418} but the nature of the receptors which mediate these effects is disputed.{9585}

Formal name: 1,9α,11α,15S-tetrahydroxyprosta-5Z,13E-diene

Synonyms:  AGN 190190|PGF2α-OH|ZK 62717

Molecular weight: 340.5

CAS: 13261-27-3

Purity: ≥98%

Formulation: A solution in methyl acetate

Product Type|Biochemicals|Lipids|Prostaglandins||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway||Research Area|Neuroscience|Ophthalmology

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