PGE3 is formed via the COX metabolism of EPA.{1145} In human ocular tissue

Prostaglandin E3 – 50 µg

Brand:
Cayman
CAS:
802-31-3
Storage:
-20
UN-No:
De Minimis - 1231 / 3

Prostaglandin E3 (PGE3) is formed via the cyclooxygenase (COX) metabolism of eicosapentaenoic acid.{1145} In human ocular tissue, it comprises 2.4% of the COX products formed.{1145} When applied to the eyes of a rabbit, a 1 µg dose of PGE3 decreases intraocular pressure from 21 mmHg to about 17 mmHg.{1225}  

 

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Description

PGE3 is formed via the COX metabolism of EPA.{1145} In human ocular tissue, it comprises 2.4% of the COX products formed.{1145} When applied to the eyes of a rabbit, a 1 µg dose of PGE3 decreases IOP from 21 mmHg to about 17 mmHg.{1225}

Formal name: 9-oxo-11α,15S-dihydroxy-prosta-5Z,13E,17Z-trien-1-oic acid

Synonyms:  PGE3

Molecular weight: 350.5

CAS: 802-31-3

Purity: ≥98%

Formulation: A solution in methyl acetate

Product Type|Biochemicals|Lipids|Prostaglandins||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway||Research Area|Neuroscience|Ophthalmology

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