A more lipophilic prodrug form of the free acid PGE2; hydrolyzed to the free acid by endogenous esterases upon in vivo administration

Prostaglandin E2 isopropyl ester – 1 mg

Brand:
Cayman
CAS:
71845-66-4
Storage:
-20
UN-No:
De Minimis - 1231 / 3

Prostaglandin E2 (PGE2) isopropyl ester is a more lipophilic form of the free acid, PGE2. PG esters have enhanced lipid solubility compared to their parent compounds. They are generally hydrolyzed to the free acid by endogenous esterases upon in vivo administration, making the esters useful prodrugs. In general, the C-1 esters of PGs show greatly diminished receptor activity in vitro compared to the parent free acids.  

 

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SKU: 10384 - 1 mg Category:

Description

A more lipophilic prodrug form of the free acid PGE2; hydrolyzed to the free acid by endogenous esterases upon in vivo administration

Formal name: 9-oxo-11α,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid, isopropyl ester

Synonyms: 

Molecular weight: 394.5

CAS: 71845-66-4

Purity: ≥98%

Formulation: A solution in methyl acetate

Product Type|Biochemicals|Lipids|Prostaglandins||Research Area|Endocrinology & Metabolism|Reproductive Biology||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Prostaglandins||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway

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