An internal standard for the quantification of PGE2 by GC- or LC-MS

Prostaglandin E2-d9 – 500 µg

Brand:
Cayman
CAS:
1356347-42-6
Storage:
-20
UN-No:
Excepted Quantity - 1231 / 3

PGE2-d9 contains nine deuterium atoms at the 17, 17’, 18, 18’, 19, 19′, 20, 20, and 20′ positions. It is intended for use as an internal standard for the quantification of PGE2 by GC- or LC-mass spectrometry (MS). PGE2 is one of the primary cyclooxygenase products of arachidonic acid and one of the most widely investigated prostaglandins. Its activity influences inflammation, fertility and parturition, gastric mucosal integrity, and immune modulation.{1585,1558,437,1330} The effects of PGE2 are transduced by at least four distinct receptors designated EP1, EP2, EP3, and EP4.{1422} Affinity constants (Kd) of PGE2 for these receptors range from 1-10 nM depending on the receptor subtype and tissue.  

 

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SKU: 10581 - 500 µg Category:

Description

An internal standard for the quantification of PGE2 by GC- or LC-MS

Formal name: 9-oxo-11α,15S-dihydroxy-prosta-5Z,13E-dien-1-oic-17,17,18,18,19,19,20,20,20-d9 acid

Synonyms:  Dinoprostone-d9|PGE2-d9

Molecular weight: 361.5

CAS: 1356347-42-6

Purity: ≥99% deuterated forms (d1-d9)

Formulation: A solution in methyl acetate

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Product Type|Biochemicals|Lipids|Prostaglandins||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Prostaglandins||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway

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