PGD2 methyl ester is a more lipid-soluble

Prostaglandin D2 methyl ester – 500 µg

Brand:
Cayman
CAS:
49852-81-5
Storage:
-20
UN-No:
De Minimis - 1231 / 3

Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is produced in large quantities by hematopoietic PGD synthase during allergic and asthmatic anaphylaxis.{416} It causes vasodilation, flushing, hypotension, and is an inhibitor of platelet aggregation.{416,580} Prostaglandin D2 methyl ester (PGD2 methyl ester) is a more lipid-soluble, cell-permeable prodrug form of PGD2.{14117} It binds to the human and mouse PGD2 receptors (DP1 and CRTH2/DP2) with 5-10 fold lower affinity than PGD2.{11494}  

 

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SKU: 10008385 - 500 µg Category:

Description

PGD2 methyl ester is a more lipid-soluble, cell-permeable prodrug form of PGD2.{14117} It binds to the human and mouse PGD2 receptors (DP1 and CRTH2/DP2) with 5-10 fold lower affinity than PGD2.{11494}

Formal name: 9α,15S-dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oic acid, methyl ester

Synonyms:  PGD2 methyl ester

Molecular weight: 366.5

CAS: 49852-81-5

Purity: ≥97%

Formulation: A solution in methyl acetate

Product Type|Biochemicals|Lipids|Prostaglandins||Research Area|Cardiovascular System|Blood|Coagulation & Hemostasis||Research Area|Cardiovascular System|Cardiovascular Diseases|Hypotension||Research Area|Cardiovascular System|Vasculature|Vasodilation||Research Area|Immunology & Inflammation|Allergy||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Prostaglandins||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Immunology & Inflammation|Pulmonary Diseases|Asthma||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway

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