A quantitative analytical standard guaranteed to meet MaxSpec® identity

Prostaglandin D2 Ethanolamide MaxSpec® Standard – 100 µg

Brand:
Cayman
CAS:
398138-28-8
Storage:
-80
UN-No:
- 1170 / 3

Prostaglandin D2 ethanolamide (PGD2-EA) is a bioactive lipid produced by the sequential metabolism of anandamide (arachidonoyl ethanolamide; Item Nos. 90050 | 10007270) by cyclooxygenase (COX) enzymes, in particular by COX-2, and PGD synthase.{11045,22752,22753} The biosynthesis of PGD2-EA from anandamide can also be increased when anandamide metabolism is diminished by deletion of fatty acid amide hydrolase.{12142} PGD2-EA is inactive against recombinant prostanoid receptors, including the D prostanoid receptor.{12144} It increases the frequency of miniature inhibitory postsynaptic currents in primary cultured hippocampal neurons, an effect which is the opposite of that induced by anandamide.{22753} PGD2-EA also induces apoptosis in colorectal carcinoma cell lines.{22752} PGD2-EA MaxSpec® standard is a quantitative grade standard of PGD2-EA (Item No. 12012) that has been prepared specifically for mass spectrometry or any application where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This PGD2-EA MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.  

 

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SKU: 10007203 - 100 µg Category:

Description

A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications,

Formal name: N-(2-hydroxyethyl)-11-oxo-9α,15S-dihydroxy-prosta-5Z,13E-dien-1-amide

Synonyms:  PGD2-EA|Prostamide D2

Molecular weight: 395.5

CAS: 398138-28-8

Purity: ≥95%

Formulation: A solution in ethanol at 100 µg/ml

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards|MaxSpec®||Product Type|Biochemicals|Lipids|Prostaglandins||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway

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