Description
Prostaglandin D synthase (PGDS) catalyzes the isomerization of PGH2 to produce PGD2. PGD2 induces sleep, regulates nociception, inhibits platelet aggregation, and acts as an allergic mediator. Two distinct types of PGDS have been identified, namely the lipocalin type enzyme (β-trace) and the hematopoietic enzyme.{8448,4387} Lipocalin-type PGDS is localized in the central nervous system, genital organs of various mammals and the human heart.{8448,5971,4388,8451} Patients with chronic renal failure and hypertension exhibit elevated amounts of lipocalin-type PGDS in serum and urine.{10440} The lipocalin-type PGDS has been identified as β-trace (~24 kDa), which is a major protein in the human cerebrospinal fluid.{4387,1543}
Synonyms: Cerebrin-28|Glutathione-independent PGD Synthase|Lipocalin-PGDS|L-PGDS|PGDS2|Prostaglandin-H2 D-isomerase|β-Trace Protein
Immunogen: Recombinant human L-PGD synthase
Formulation: 200 µg of ion-exchange chromatography purified antibody
Isotype: IgG1κ
Applications: IHC and WB
Origin: Animal/Rat
Stability: 365 days
Application|Immunohistochemistry||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Immunology & Inflammation|Allergy||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway
