PGB3 is a non-enzymatic dehydration product resulting from the treatment of PGE3 with strong base. In a structure-activity binding study to determine the affinity of various prostaglandins to human PPARγ

Prostaglandin B3 – 100 µg

Brand:
Cayman
CAS:
36614-32-1
Storage:
-20
UN-No:
De Minimis - 1231 / 3

Prostaglandin B3 (PGB3) is a non-enzymatic dehydration product resulting from the treatment of Prostaglandin E3 (PGE3) with strong base. In a structure-activity binding study to determine the affinity of various prostaglandins to human PPARγ, PGB3 exhibited a Ki value greater than 1 mM.{11138} In contrast, PGB1 and PGB2 showed significantly higher affinity for PPARγ, with Ki values of 26 and 77 µM, respectively, the same assay.  

 

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SKU: 11990 - 100 µg Category:

Description

PGB3 is a non-enzymatic dehydration product resulting from the treatment of PGE3 with strong base. In a structure-activity binding study to determine the affinity of various prostaglandins to human PPARγ, PGB3 exhibited a Ki value greater than 1 mM.{11138} In contrast, PGB1 and PGB2 showed significantly higher affinity for PPARγ, with Ki values of 26 and 77 µM, respectively, the same assay.

Formal name: 9-oxo-15S-hydroxy-prosta-5Z,8(12),13E,17Z-tetraen-1-oic acid

Synonyms:  PGB3

Molecular weight: 332.4

CAS: 36614-32-1

Purity: >97%

Formulation: A solution in methyl acetate

Product Type|Biochemicals|Lipids|Prostaglandins||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway

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