PGA1 was first isolated as a dehydration product of the PGE1 compounds found in human semen.{411} It has been shown to cause renal vasodilation

Prostaglandin A1 – 5 mg

Brand:
Cayman
CAS:
14152-28-4
Storage:
-20
UN-No:
Non-Hazardous - /

Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen.{411} It has been shown to cause renal vasodilation, increased urine sodium excretion, and lowered arterial pressure in hypertensive patients.{410} It also has growth-inhibitory activity on tumor cells; the IC50 value for the inhibition of human ovarian cancer is 7.5 µM.{1349}  

 

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Description

PGA1 was first isolated as a dehydration product of the PGE1 compounds found in human semen.{411} It has been shown to cause renal vasodilation, increased urine sodium excretion, and lowered arterial pressure in hypertensive patients.{410} It also has growth-inhibitory activity on tumor cells; the IC50 value for the inhibition of human ovarian cancer is 7.5 µM.{1349}

Formal name: 9-oxo-15S-hydroxy-prosta-10,13E-dien-1-oic acid

Synonyms:  PGA1

Molecular weight: 336.5

CAS: 14152-28-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Lipids|Prostaglandins||Research Area|Cancer||Research Area|Cardiovascular System|Cardiovascular Diseases|Hypertension||Research Area|Cardiovascular System|Kidney & Renal Disease||Research Area|Cardiovascular System|Vasculature|Vasodilation||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway

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