Description
A broad-spectrum triazole fungicide; inhibits the conversion of lanosterol to ergosterol, leading to fungal cell membrane disruption; inhibits S. cerevisiae, but not rat liver, microsomal cytochrome P450 (IC50s = 0.04 and >200 µM, respectively); inhibits the growth of T. deformans and R. stolonifer (EC50s = 0.073 and 4.6 µg/ml, respectively), as well as A. niger, M. fructigena, S. nodorum, T. harzanium, R. solani, and S. rolfsii from 0.1 to 5 ppm; increases the weight of seminal vesicles and vas deferens, as well as the percentage of sperm with abnormal tail morphology, and decreases the plasma concentration of estradiol in male rats at 4 mg/kg; increases production of ROS, the number of DNA mutations, and the incidence of tumor formation in mouse liver
Formal name: 1-[[2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan-2-yl]methyl]-1H-1,2,4-triazole
Synonyms: CGA 64250
Molecular weight: 342.2
CAS: 60207-90-1
Purity: ≥95% (mixture of isomers)
Formulation: A neat oil
Product Type|Biochemicals|Pesticides|Fungicides||Product Type|Biochemicals|Small Molecule Inhibitors|Cytochrome P450||Product Type|Biochemicals|Small Molecule Inhibitors|Sterol Biosynthesis||Research Area|Endocrinology & Metabolism|Reproductive Biology||Research Area|Immunology & Inflammation||Research Area|Oxidative Stress & Reactive Species|Pro-oxidant Activity||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen||Research Area|Toxicology|Environmental|Agriculture
