Description
A neuropeptide involved in regulating food intake; an agonist of GPR10/hGR3 and hNPFF2 (Kis = 1 and 19 nM, respectively); stimulates calcium mobilization in cells expressing GPR10 (EC50 = 1.5 nM); increases the release of GnRH, VIP, and galanin from rat medial basal hypothalamic explants at 100 nM; increases plasma levels of luteinizing hormone, follicle stimulating hormone, and testosterone in male rats at 5 nmol; reduces food intake in fasted rats to 58.4, 53.4, and 55.4% of control levels at 1, 5, and 10 nmol, respectively
Formal name: L-seryl-L-arginyl-L-threonyl-L-histidyl-L-arginyl-L-histidyl-L-seryl-L-methionyl-L-α-glutamyl-L-isoleucyl-L-arginyl-L-threonyl-L-prolyl-L-α-aspartyl-L-isoleucyl-L-asparaginyl-L-prolyl-L-alanyl-L-tryptophyl-L-tyrosyl-L-alanyl-L-seryl-L-arginylglycyl-L-isoleucyl-L-arginyl-L-prolyl-L-valylglycyl-L-arginyl-L-phenylalaninamide
Synonyms: Human PrRP-31|PrRP(1-31)
Molecular weight: 3,664.20
CAS: 215510-22-8
Purity: ≥95%
Formulation: A lyophilized powder
Product Type|Biochemicals|Peptides|Neuropeptides||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Endocrinology & Metabolism|Hormones & Receptors||Research Area|Endocrinology & Metabolism|Reproductive Biology
