The biosynthetic precursor of all other steroid hormones; activates the human progesterone receptor with an EC50 value of 0.5 nM

Progesterone – 1 g

Brand:
Cayman
CAS:
57-83-0
Storage:
-20
UN-No:
Non-Hazardous - /

Progesterone, along with pregnenolone, is the biosynthetic precursor of all other steroid hormones. Progesterone is synthesized from cholesterol by the sequential action of desmolase in the mitochondria, which produces pregnenolone, followed by Δ4,5-isomerase in the outer mitochondrial membrane and smooth endoplasmic reticulum of steroid-secreting cells.{8458} Progesterone activates the human progesterone receptor with an EC50 value of 0.5 nM.{25839}  

 

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Description

The biosynthetic precursor of all other steroid hormones; activates the human progesterone receptor with an EC50 value of 0.5 nM

Formal name: pregn-4-ene-3,20-dione

Synonyms:  Crinone®|Cyclogest|Endometrin®|NSC 64377|NSC 9704|Utrogestan®

Molecular weight: 314.5

CAS: 57-83-0

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Lipids|Sterol Lipids||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Endocrinology & Metabolism|Hormones & Receptors|Estrogens & Progestins

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