A phenol with diverse biological activities; inhibits MCF-7 breast cancer cell proliferation (IC50 = 19.2 µM); scavenges DPPH and superoxide anion radicals in cell-free assays; inhibits LDL oxidation in vitro at 5 and 10 µM; prevents carbon tetrachloride-induced increases in serum AST and ALT activities and hepatic injury in mice at 100 mg/kg

Procyanidin B2 – 1 mg

Brand:
Cayman
CAS:
29106-49-8
Storage:
-20
UN-No:
Non-Hazardous - /

Procyanidin B2 is a phenol and a dimer of (–)-epicatechin (Item No. 11807) that has been found in apple pomace and has diverse biological activities.{54438,54439,54440,54441} It inhibits MCF-7 breast cancer cell proliferation (IC50 = 19.2 µM).{54438} Procyanidin B2 scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) and superoxide anion radicals in cell-free assays.{54439} It inhibits LDL oxidation in vitro by 79.5 and 98% when used at concentrations of 5 and 10 µM, respectively.{54440} Procyanidin B2 (100 mg/kg) prevents carbon tetrachloride-induced increases in serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) activities and hepatic injury in mice.{54441}  

 

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SKU: 19865 - Category:

Description

A phenol with diverse biological activities; inhibits MCF-7 breast cancer cell proliferation (IC50 = 19.2 µM); scavenges DPPH and superoxide anion radicals in cell-free assays; inhibits LDL oxidation in vitro at 5 and 10 µM; prevents carbon tetrachloride-induced increases in serum AST and ALT activities and hepatic injury in mice at 100 mg/kg

Formal name: (2R,2’R,3R,3’R,4R)-2,2′-bis(3,4-dihydroxyphenyl)-3,3′,4,4′-tetrahydro-[4,8′-bi-2H-1-benzopyran]-3,3′,5,5′,7,7′-hexol

Synonyms:  (−)-Epicatechin-(4β→8)-(−)-epicatechin|Proanthocyanidin B2

Molecular weight: 578.5

CAS: 29106-49-8

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Catechins||Product Type|Biochemicals|Natural Products|Polyphenols||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Cancer||Research Area|Cardiovascular System|Lipids & Lipoproteins|Lipoproteins||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Lipid Peroxidation||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen|Non-enzymatic

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