A fungal metabolite with diverse biological activities; an intermediate in the biosynthesis of viridicatumtoxin; active against MRSA and vancomycin-resistant E. faecalis (IC50s = 4.4 and 4.8 μM

Previridicatumtoxin – 1 mg

Brand:
Cayman
CAS:
1379585-81-5
Storage:
-20
UN-No:
Non-Hazardous - /

Previridicatumtoxin is a fungal metabolite that has been found in P. aethiopicum and has diverse biological activities.{49626,49627} It is an intermediate in the biosynthesis of the mycotoxin viridicatumtoxin (Item No. 25480). Previridicatumtoxin is active against methicillin-resistant S. aureus (MRSA) and vancomycin-resistant E. faecalis (IC50s = 4.4 and 4.8 μM, respectively), as well as C. albicans and S. cerevisiae (MIC = 32 μg/ml for both).{49627,49626} It is cytotoxic to NCI H460, KB-3-1, and SW620 cancer cells (IC50s = 5.3, 4.1, and 6 μM, respectively).{49627}  

 

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SKU: 29069 - 1 mg Category:

Description

A fungal metabolite with diverse biological activities; an intermediate in the biosynthesis of viridicatumtoxin; active against MRSA and vancomycin-resistant E. faecalis (IC50s = 4.4 and 4.8 μM, respectively), as well as C. albicans and S. cerevisiae (MIC = 32 μg/ml for both); cytotoxic to NCI H460, KB-3-1, and SW620 cancer cells (IC50s = 5.3, 4.1, and 6 μM, respectively)

Formal name: (4aS,5S,12aS)-6-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-1,4,4a,5,12,12a-hexahydro-3,4a,5,10,11,12a-hexahydroxy-8-methoxy-1,12-dioxo-2-naphthacenecarboxamide

Synonyms: 

Molecular weight: 567.6

CAS: 1379585-81-5

Purity: ≥70%

Formulation: A solid

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