A metabolite of pravastatin; formed when pravastatin undergoes acid catalyzed non-enzymatic lactonization in the stomach

Pravastatin lactone – 10 mg

Brand:
Cayman
CAS:
85956-22-5
Storage:
-20
UN-No:
Non-Hazardous - /

Pravastatin lactone is a metabolite of pravastatin (Item No. 10010342), a hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor that is a ring-hydroxylated metabolite of mevastatin (Item No. 10010340).{15312,38252} Pravastatin lactone is formed when pravastatin undergoes acid-catalyzed non-enzymatic lactonization in the stomach following oral administration.{38252}  

 

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Description

A metabolite of pravastatin; formed when pravastatin undergoes acid catalyzed non-enzymatic lactonization in the stomach ,

Formal name: (2S)-2-methyl-butanoic acid, (1S,3S,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3-hydroxy-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester

Synonyms:  R-414|SQ 31,369

Molecular weight: 406.5

CAS: 85956-22-5

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Toxicology|Drug Metabolism|Drug Metabolites

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