A prodrug form of R-99224; inhibits ex vivo washed platelet aggregation in rat platelet rich-plasma at 0.3 and 3 mg/kg; prevents thrombus formation (ED50 = 0.68 mg/kg) and increases tail bleeding time in rats

Prasugrel – 100 mg

Brand:
Cayman
CAS:
150322-43-3
Storage:
-20
UN-No:
Non-Hazardous - /

Prasugrel is a prodrug form of the platelet purinergic P2Y12 receptor antagonist R-99224.{23698} Prasugrel (0.3 and 3 mg/kg) inhibits ex vivo washed platelet aggregation in rat platelet rich-plasma.{23697} In vivo, prasugrel prevents thrombus formation (ED50 = 0.68 mg/kg) and increases tail bleeding time in rats. Formulations containing prasugrel have been used in the prevention of blood clots.  

 

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Description

A prodrug form of R-99224; inhibits ex vivo washed platelet aggregation in rat platelet rich-plasma at 0.3 and 3 mg/kg; prevents thrombus formation (ED50 = 0.68 mg/kg) and increases tail bleeding time in rats

Formal name: 2-[2-(acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-cyclopropyl-2-(2-fluorophenyl)-ethanone

Synonyms:  CS 747|LY640315

Molecular weight: 373.4

CAS: 150322-43-3

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Cardiovascular System|Blood|Coagulation & Hemostasis||Research Area|Cardiovascular System|Blood|Thrombosis

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