Description
PPARγ is a ligand-activated transcription factor involved in the regulation of lipid homeostasis and may function as a master regulator of adipogenesis.{2160,6619,6620,4136} PPARγ mRNA is expressed prominently in adipose tissue, but is also found in large intestine, kidney, liver, and small intestine.{4980} Alternative splicing of the PPARγ gene results in at least two mRNA species that differ at their 5′ ends.{2160,4540} Human PPARγ1 and PPARγ2 proteins are 53 and 57 kDa, respectively, based on the deduced amino acid sequences.{4540} PPARγ2 is the major PPARγ isoform found in both the cytosolic and nuclear fractions of undifferentiated 3T3-L1 cells.{7027} Total cellular PPARγ2 protein increases approximately 2-fold following differentiation of 3T3-L1 cells, whereas only small quantities of PPARγ1 are detected in the nuclear fraction following differentiation.{7027}
Synonyms: Peroxisome Proliferator-activated Receptor γ
Immunogen: Synthetic peptide from the internal region of PPARγ1
Formulation: 500 µl of Peptide affinity-purified antibody
Isotype:
Applications: IHC, IP, and WB
Origin: Animal/Rabbit
Stability: 365 days
Application|Immunohistochemistry||Application|Immunoprecipitation||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Endocrinology & Metabolism|Hormones & Receptors|PPARs
