A flavonoid glycoside; inhibits the growth of SGC-7901 gastric cancer cells from 5-25 µg/ml; inhibits LPS-induced NF-κB DNA-binding activity

Poncirin – 5 mg

Brand:
Cayman
CAS:
14941-08-3
Storage:
-20
UN-No:
Non-Hazardous - /

Poncirin is a flavonoid glycoside that has been found in P. trifoliata and has diverse biological activities.{60090,60091,60092,60103} It inhibits the growth of SGC-7901 gastric cancer cells when used at concentrations ranging from 5 to 25 µg/ml.{60091} Poncirin (25-100 µM) inhibits LPS-induced NF-κB DNA-binding activity, as well as production of nitric oxide (NO) and prostaglandin E2 (PGE2; Item No. 14010) in RAW 264.7 cells.{60092} It reduces the gastric ulcer lesion index in a rat model of HCl/ethanol-induced gastritis when administered at doses of 50 and 100 mg/kg.{60103}  

 

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SKU: 31706 - 5 mg Category:

Description

A flavonoid glycoside; inhibits the growth of SGC-7901 gastric cancer cells from 5-25 µg/ml; inhibits LPS-induced NF-κB DNA-binding activity, as well as NO and PGE2 production in RAW 264.7 cells from 25-100 µM; reduces the gastric ulcer lesion index in a rat model of HCl/ethanol-induced gastritis at 50 and 100 mg/kg ,,

Formal name: (2S)-7-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one

Synonyms: 

Molecular weight: 594.6

CAS: 14941-08-3

Purity: ≥98%

Formulation: A solid

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