A sesquiterpene dialdehyde noted for its broad antifungal properties; cytotoxic against bacteria

Polygodial – 1 mg

Brand:
Cayman
CAS:
6754-20-7
Storage:
-20
UN-No:
Non-Hazardous - /

Polygodial is a sesquiterpene dialdehyde isolated from the leaves of certain peppers and related plants. Noted for its broad antifungal properties, polygodial is also cytotoxic against bacteria, algae, and sea squirts.{23936,23937,23934} In mammals, polygodial produces a pungent flavor, activates the transient receptor potential cation channel TRPA1 (EC50 = 59 nM), and produces antinociception.{23938,23935}  

 

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Description

A sesquiterpene dialdehyde noted for its broad antifungal properties; cytotoxic against bacteria, algae, and sea squirts; in mammals, produces a pungent flavor, activates TRPA1 (EC50 = 59 nM), and produces antinociception

Formal name: (1R,4aS,8aS)-1,4,4a,5,6,7,8,8a-octahydro-5,5,8a-trimethyl-1,2-naphthalenedicarboxaldehyde

Synonyms:  Tadeonal

Molecular weight: 234.3

CAS: 6754-20-7

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Antifungals||Product Type|Biochemicals|Ion Channel Modulation|Activators||Product Type|Biochemicals|Natural Products|Terpenes||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases||Research Area|Infectious Disease|Fungal Diseases||Research Area|Neuroscience|Pain Research

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