Pluviatolide – 1 mg

Brand:
Cayman
CAS:
28115-68-6
Storage:
-20
UN-No:
Non-Hazardous - /

Pluviatolide is a lignan that has been found in B. chinense and has diverse biological activities, including antioxidant, enzyme inhibitory, and antispasmodic properties.{45352,45671,45672} It scavenges ABTS (Item No. 27317) and 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in cell-free assays (IC50s = 23.2 and 88.5 µM, respectively).{45352} Pluviatolide inhibits matrix metalloproteinase-7 (MMP-7) with an IC50 value of 260 µM.{45671} It decreases contractions induced by acetylcholine (Item No. 23829) in isolated guinea pig ileum when used at concentrations of 30 and 100 µM.{45672}  

 

Available on backorder

SKU: 29582 - 1 mg Category:

Description

A lignan; scavenges ABTS and DPPH radicals in cell-free assays (IC50s = 23.2 and 88.5 µM, respectively); inhibits MMP-7 (IC50 = 260 µM); decreases acethylcholine-induced contractions in isolated guinea pig ileum at 30 and 100 µM


Formal name: (3R,4R)-4-(1,3-benzodioxol-5-ylmethyl)dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-2(3H)-furanone

Synonyms:  (–)-Pluviatolide

Molecular weight: 356.4

CAS: 28115-68-6

Purity: ≥95%

Formulation: A solid