A specific cGMP-dependent PKG inhibitor (Ki = 86 µM); a nonphosphorylatable synthetic peptide analogous to a substrate corresponding to the serine-32 phosphorylation site in histone H2B

PKG Inhibitor – 1 mg

Brand:
Cayman
CAS:
82801-73-8
Storage:
-20
UN-No:
Non-Hazardous - /

PKG inhibitor is a specific cGMP-dependent PKG inhibitor (Ki = 86 µM).{26244} This synthetic peptide is a nonphosphorylatable analog of a substrate corresponding to the serine-32 phosphorylation site in histone H2B.{26244} PKG inhibitor has been reported to block cGMP-dependent NMDA potentiation and nitric oxide-induced depression of GABA currents in cultured retinal amacrine cells.{26245}  

 

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Description

A specific cGMP-dependent PKG inhibitor (Ki = 86 µM); a nonphosphorylatable synthetic peptide analogous to a substrate corresponding to the serine-32 phosphorylation site in histone H2B

Formal name: L-arginyl-L-lysyl-L-arginyl-L-alanyl-L-arginyl-L-lysyl-L-glutamic acid

Synonyms:  Arginyl-lysyl-arginyl-alanyl-arginyl-lysyl-glutamic acid|Protein Kinase G Inhibitor

Molecular weight: 943.1

CAS: 82801-73-8

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Kinase Inhibitors|PKD & PKG||Product Type|Biochemicals|Peptides||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cell Biology|Cell Signaling|cGMP Signaling||Research Area|Neuroscience

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