A class I antiarrhythmic agent; lengthens the final repolarization of action potentials in isolated rabbit ventricular myocytes and inhibits tachyarrhythmias induced by prolonged afterdepolarizations in isolated guinea pig papillary muscles at 5 µM; suppresses ouabain- or epinephrine-induced ventricular arrhythmias and aconitine-induced atrial arrhythmias in dogs at 2.5 and 5 mg/kg

Pirmenol – 1 mg

Brand:
Cayman
CAS:
68252-19-7
Storage:
-20
UN-No:
Non-Hazardous - /

Pirmenol is a class I antiarrhythmic agent.{53631,53632,53633} It lengthens the final repolarization of action potentials in isolated rabbit ventricular myocytes and inhibits tachyarrhythmias induced by prolonged afterdepolarizations in isolated guinea pig papillary muscles when used at a concentration of 5 µM.{53631} Pirmenol (2.5 and 5 mg/kg) suppresses ouabain- or epinephrine-induced ventricular arrhythmias and aconitine-induced atrial arrhythmias in dogs.{53632,53633}  

 

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SKU: 29042 - 1 mg Category:

Description

A class I antiarrhythmic agent; lengthens the final repolarization of action potentials in isolated rabbit ventricular myocytes and inhibits tachyarrhythmias induced by prolonged afterdepolarizations in isolated guinea pig papillary muscles at 5 µM; suppresses ouabain- or epinephrine-induced ventricular arrhythmias and aconitine-induced atrial arrhythmias in dogs at 2.5 and 5 mg/kg

Formal name: rel-α-[3-[(2R,6S)-2,6-dimethyl-1-piperidinyl]propyl]-α-phenyl-2-pyridinemethanol

Synonyms:  (±)-Pirmenol

Molecular weight: 338.5

CAS: 68252-19-7

Purity: ≥98%

Formulation: A solid

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