An α2-AR antagonist (Kis = 5.4

Piperoxan (hydrochloride) – 5 mg

Brand:
Cayman
CAS:
135-87-5
Storage:
-20
UN-No:
Non-Hazardous - /

Piperoxan is an α2-adrenergic receptor (α2-AR) antagonist (Kis = 5.4, 2, and 1.3 nM for α2A-, α2B-, and α2C-ARs, respectively) and a first generation histamine receptor antagonist.{49273,49274} It reverses decreases in systolic blood pressure induced by clonidine (Item No. 15949) in spontaneously hypertensive rats when administered at a dose of 10 mg/kg.{49275}  

 

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SKU: 27629 - 5 mg Category:

Description

An α2-AR antagonist (Kis = 5.4, 2, and 1.3 nM for α2A-, α2B-, and α2C-ARs, respectively); reverses decreases in systolic blood pressure induced by clonidine in spontaneously hypertensive rats at 10 mg/kg

Formal name: 1-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]-piperidine, monohydrochloride

Synonyms:  DL-Piperoxan

Molecular weight: 269.8

CAS: 135-87-5

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Cardiovascular System|Cardiovascular Diseases|Hypotension

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