A lignan with diverse biological activities; inhibits peroxidation of a linoleic acid emulsion by 64.2% at 20 μg/ml

Pinoresinol Diglucoside – 25 mg

Brand:
Cayman
CAS:
63902-38-5
Storage:
-20
UN-No:
Non-Hazardous - /

Pinoresinol diglucoside is a lignan that has been found in E. ulmoides and has diverse biological activities.{51136,51137,51138} It inhibits peroxidation of a linoleic acid emulsion by 64.2% when used at a concentration of 20 μg/ml, scavenges hydrogen peroxide and 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805), ABTS (Item No. 27317), and superoxide anion free radicals, and has ferrous ion metal chelating activity in cell-free assays.{51136} In vivo, pinoresinol diglucoside (10, 20, and 40 mg/kg) inhibits increases in serum levels of inorganic phosphate, IL-6, and TNF-α and decreases in serum calcium levels and transverse diameter, weight, bone mineral content, and bone mineral density of the right femur in a rat model of osteoporosis induced by dexamethasone (Item No. 11015).{51138}  

 

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SKU: 27708 - 25 mg Category:

Description

A lignan with diverse biological activities; inhibits peroxidation of a linoleic acid emulsion by 64.2% at 20 μg/ml, scavenges hydrogen peroxide and DPPH, ABTS, and superoxide anion free radicals, and has ferrous ion metal chelating activity in cell-free assays; inhibits increases in serum levels of inorganic phosphate, IL-6, and TNF-α and decreases in serum calcium levels and transverse diameter, weight, bone mineral content, and bone mineral density of the right femur in a rat model of osteoporosis induced by dexamethasone at 10, 20, and 40 mg/kg

Formal name: [(1S,3aR,4S,6aR)-tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis(2-methoxy-4,1-phenylene) bis-β-D-glucopyranoside

Synonyms:  (+)-Pinoresinol di-O-β-D-glucopyranoside

Molecular weight: 682.7

CAS: 63902-38-5

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Metal Chelators||Product Type|Biochemicals|Natural Products|Lignans||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Endocrinology & Metabolism|Bone Growth & Remodeling||Research Area|Immunology & Inflammation||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Lipid Peroxidation||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen|Non-enzymatic

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