Description
A potent inhibitor of the PI3K catalytic subunit p110δ (IC50s = 10,000, 490, 10, and 160 nM, for p110 subunit isoforms α, β, δ, and γ, respectively); selective for PI3K p110 subunit isoforms over DNA-PK, mTOR, and eight tyrosine kinases; inhibits chemokinetic and chemotactic migration of neutrophils induced by CXCL8
Formal name: 2-[[4-amino-3-(3-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone
Synonyms:
Molecular weight: 489.5
CAS: 900185-02-6
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Kinase Inhibitors|PI3K||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cell Biology|Cell Signaling|PI3K/Akt/mTOR Signaling
