A natural

Picrotoxin – 5 g

Brand:
Cayman
CAS:
124-87-8
Storage:
-20
UN-No:
Excepted Quantity - 3462 / 6.1

Picrotoxin is a natural plant-derived poison that acts as a selective GABAA receptor antagonist.{32532,32535} It is functional in vivo and is used to study the role of GABAA receptors in the central nervous system as well in the periphery.{32533,32534} Picrotoxin induces seizures in adult and immature animals and is used to study GABAA-dependent seizures and drugs that block this pathway.{32536}  

 

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Description

A natural, selective GABAA receptor antagonist; functional in vivo; induces seizures in adult and immature animals

Formal name: (1aR,2aR,3S,6R,6aS,8aS,8bR,9R)-hexahydro-2a-hydroxy-8b-methyl-9-(1-methylethenyl)-3,6-methano-8H-1,5,7-trioxacyclopenta[ij]cycloprop[a]azulene-4,8(3H)-dione compd. with (1aR,2aR,3S,6R,6aS,8aS,8bR,9S)-hexahydro-2a-hydroxy-9-(1-hydroxy-1-methylethyl)-8b-methyl-3,6-methano-8H-1,5,7-trioxacyclopenta[ij]cycloprop[a]azulene-4,8(3H)-dione

Synonyms:  Cocculin|NSC 403139

Molecular weight: 602.6

CAS: 124-87-8

Purity: ≥98% (mixture of Picrotin and Picrotoxinin)

Formulation: A crystalline solid

Product Type|Biochemicals|Ion Channel Modulation|Blockers||Product Type|Biochemicals|Toxins||Research Area|Neuroscience|Seizure Disorders

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