A natural iridoid glycoside that blocks changes in acid phosphatase activity

Picroside I – 25 mg

Brand:
Cayman
CAS:
27409-30-9
Storage:
-20
UN-No:
Non-Hazardous - /

Picroliv is a hepatoprotective mixture of compounds that is isolated from an herb native to the Himalayas.{18586} Picroside I is an iridoid glycoside found in picroliv.{18586} By itself, picroside I blocks changes in acid phosphatase activity, phospholipid levels, and lipid peroxide production induced by D-galactosamine in rat liver.{25374} Picroside I also enhances neurite outgrowth in PC12D cells induced by basic fibroblast growth factor and 7S nerve growth factor when given at 60 μM.{25371,25372} At concentrations as low as 5 μM, picroside I enhances the ATPase activity of the efflux transporter P-glycoprotein.{25373}  

 

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Description

A natural iridoid glycoside that blocks changes in acid phosphatase activity, phospholipid levels, and lipid peroxide production induced by D-galactosamine in rat liver; also enhances neurite outgrowth in PC12D cells induced by bFGF and 7S NGF when given at 60 μM,,

Formal name: 6-[(2E)-3-phenyl-2-propenoate]-1aS,1bS,2S,5aR,6S,6aS-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl-β-D-glucopyranoside

Synonyms:  6’-Cinnamoylcatalpol

Molecular weight: 492.5

CAS: 27409-30-9

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Glycosides||Product Type|Biochemicals|Transporter & Exchanger Modulators||Research Area|Neuroscience||Research Area|Toxicology|Drug Metabolism

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