An antiplatelet drug that inhibits both TXA2 receptors (Kd = 325 nM) and TXA2 synthase; significantly inhibits basal and LPS-stimulated TXA2 synthesis by rat peritoneal macrophages when used at 0.5 mM

Picotamide – 25 mg

Brand:
Cayman
CAS:
32828-81-2
Storage:
-20
UN-No:
Non-Hazardous - /

Picotamide is an antiplatelet drug that inhibits both thromboxane A2 (TXA2) receptors (Kd = 325 nM) and TXA2 synthase.{34208,34210} It significantly inhibits basal and lipopolysaccharide-stimulated TXA2 synthesis by rat peritoneal macrophages when used at 0.5 mM.{34209} Formulations containing picotamide have potential applications in the reduction of peripheral artery disease in patients with diabetes.{34208}  

 

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Description

An antiplatelet drug that inhibits both TXA2 receptors (Kd = 325 nM) and TXA2 synthase; significantly inhibits basal and LPS-stimulated TXA2 synthesis by rat peritoneal macrophages when used at 0.5 mM

Formal name: 4-methoxy-N1,N3-bis(3-pyridinylmethyl)-1,3-benzenedicarboxamide

Synonyms: 

Molecular weight: 376.4

CAS: 32828-81-2

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Cardiovascular System|Blood|Coagulation & Hemostasis||Research Area|Cardiovascular System|Blood|Thrombosis||Research Area|Cardiovascular System|Cardiovascular Diseases||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway

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