A resveratrol analog that exhibits potent anticancer properties; induces apoptosis in BJAB Burkitt-like lymphoma cells with an ED50 value of 25 µM

Piceatannol – 10 mg

Brand:
Cayman
CAS:
10083-24-6
Storage:
-20
UN-No:
Non-Hazardous - /

Resveratrol is a potent phenolic antioxidant found in the skin of grapes and red wine that has anti-proliferative, anti-inflammatory, and cardioprotective properties.{9146} Piceatannol is a resveratrol analog formed by the cytochrome P450-catalyzed hydroxylation of resveratrol.{15736} Piceatannol exhibits potent anticancer properties by inducing apoptosis in BJAB Burkitt-like lymphoma cells with an ED50 value of 25 µM.{15733} Piceatannol also exhibits anti-proliferative and anti-inflammatory effects by inhibiting the activity of a wide range of tyrosine and serine/threonine protein kinases and suppressing NF-κB activation through inhibition of IκBα kinase.{15735,15734}  

 

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SKU: 10009366 - 10 mg Category:

Description

A resveratrol analog that exhibits potent anticancer properties; induces apoptosis in BJAB Burkitt-like lymphoma cells with an ED50 value of 25 µM

Formal name: 4-[(1E)-2-(3,5-dihydroxyphenyl)ethenyl]-1,2-benzenediol

Synonyms:  trans-3,3′,4,5′-Tetrahydroxystilbene|trans-Picetannol|Astringenin

Molecular weight: 244.2

CAS: 10083-24-6

Purity: >98%

Formulation: A crystalline solid

Product Type|Biochemicals|Kinase Inhibitors||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Cancer|Cell Signaling|NF-κB Signaling||Research Area|Cancer|Transcription Factors|NF-κB||Research Area|Immunology & Inflammation

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