A potent inhibitor of PI3K (IC50s = 9.8

PI-828 – 10 mg

Brand:
Cayman
CAS:
942289-87-4
Storage:
-20
UN-No:
Non-Hazardous - /

PI-828 is a potent inhibitor of phosphatidylinositol 3-kinase (PI3K; IC50s = 9.8, 183, 227, and 1,967 nM for p110β, p110α, p110δ, and p110γ, respectively).{38012} This molecule has been immobilized on epoxy-containing solid surface via the 4’amine for binding studies and shown to interact with non-PI3K cellular proteins such as mTOR, ALDH1, BRD4, CKIIα, and GSK-3β.  

 

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Description

A potent inhibitor of PI3K (IC50s = 9.8, 183, 227, and 1,967 nM for p110β, p110α, p110δ, and p110γ, respectively); has been immobilized on solid surface; interacts with non-PI3K cellular proteins such as mTOR, ALDH1, BRD4, CKIIα, and GSK-3β.

Formal name: 8-(4-aminophenyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one

Synonyms: 

Molecular weight: 322.4

CAS: 942289-87-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Kinase Inhibitors|PI3K||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cell Biology|Cell Signaling|PI3K/Akt/mTOR Signaling

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