A sphingolipid; metabolized to odd-numbered fatty acids with 2-hydroxy palmitic acid as an intermediate; induces cell death in vitro; inhibits carbachol-induced PLD activation in CHO cells transfected with C. elegans muscarinic acetylcholine receptors; essential in the yeast heat stress response

Phytosphingosine – 50 mg

Brand:
Cayman
CAS:
554-62-1
Storage:
-20
UN-No:
Non-Hazardous - /

Phytosphingosine is a sphingolipid with a hydroxyl group at the C4 position that is found mainly in fungi and plants but also in animals, including humans.{39177,39179} It is metabolized to odd-numbered fatty acids with 2-hydroxy palmitic acid (Item No. 22679) as an intermediate.{39084} Phytosphingosine dose-dependently induces cell death of CHO cells and inhibits carbachol-induced activation of phospholipase D (PLD) in CHO cells transfected with C. elegans muscarinic acetylcholine receptors.{39105} It is essential in the heat stress response in S. cerevisiae.{13592} [Matreya, LLC. Catalog No. 1330]  

 

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Description

A sphingolipid; metabolized to odd-numbered fatty acids with 2-hydroxy palmitic acid as an intermediate; induces cell death in vitro; inhibits carbachol-induced PLD activation in CHO cells transfected with C. elegans muscarinic acetylcholine receptors; essential in the yeast heat stress response,

Formal name: 2S-amino-1,3S,4R-octadecanetriol

Synonyms:  D-ribo Phytosphingosine

Molecular weight: 317.5

CAS: 554-62-1

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Lipids|Sphingolipids||Research Area|Cell Biology|Cell Death||Research Area|Cell Biology|Endomembrane System & Vesicular Trafficking||Research Area|Lipid Biochemistry|Sphingolipids

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