A reversible ChE inhibitor that inhibits both AChE and BChE (IC50s = 28 and 16 nM

Physostigmine – 100 mg

Brand:
Cayman
CAS:
57-47-6
Storage:
-20
UN-No:
De Minimis - 1544 / 6.1

Physostigmine is a natural, reversible cholinesterase (ChE) inhibitor that inhibits both acetyl ChE and butyryl ChE (IC50s = 28 and 16 nM, respectively).{24084,24085} ChE inhibitors, including physostigmine, have potential value in ameliorating dementia associated with neurodegenerative diseases.{18344,23018,24086,24083}  

 

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SKU: 13027 - 100 mg Category:

Description

A reversible ChE inhibitor that inhibits both AChE and BChE (IC50s = 28 and 16 nM, respectively)

Formal name: 1,2,3,3aS,8,8aR-hexahydro-1,3a,8-trimethyl-pyrrolo[2,3-b]indol-5-ol, 5-(N-methylcarbamate)

Synonyms:  (-)-Physostigmine|Eserine|MCV 4484|NIH 10421|NSC 30782

Molecular weight: 275.4

CAS: 57-47-6

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products||Product Type|Biochemicals|Small Molecule Inhibitors|Acetylcholine Turnover||Research Area|Neuroscience|Neurodegenerative Disorders|Alzheimer’s Disease||Research Area|Neuroscience|Neurodegenerative Disorders|Parkinson’s Disease

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