A red dye that can be used as an alternative to Gram staining; inhibits MRSA growth in vitro at 100 µg/ml; modulates channel activity of wild-type CFTR (Ki = 38 µM) and mutant delta F508 CFTR (Ki = 33 µM)

Phloxine B – 100 g

Brand:
Cayman
CAS:
18472-87-2
Storage:
-20
UN-No:
Non-Hazardous - /

Phloxine B is a red dye, the USP grade of which is used as a color additive for food, drugs, and cosmetics.{22804} It has also been used as an alternative to Gram staining, to differentiate between Gram-negative and Gram-positive bacteria.{30296} At 100 µg/ml, it can inhibit methicillin-resistant S. aureus growth in vitro.{30297} Phloxine B has also been shown to modulate channel activity of wild-type cystic fibrosis transmembrane conductance regulator chloride channels (CFTR; Ki = 38 µM) and mutant delta F508 CFTR (Ki = 33 µM).{30295}  

 

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Description

A red dye that can be used as an alternative to Gram staining; inhibits MRSA growth in vitro at 100 µg/ml; modulates channel activity of wild-type CFTR (Ki = 38 µM) and mutant delta F508 CFTR (Ki = 33 µM)

Formal name: 2′,​4′,​5′,​7′-​tetrabromo-​4,​5,​6,​7-​tetrachloro-​​3′,​6′-​dihydroxy-​​spiro[isobenzofuran-​​1(3H)​,​9′-​[9H]​xanthen]​-​​3-​one, disodium salt

Synonyms:  Acid Red 92|Cyanosine|D&C Red No. 28

Molecular weight: 829.6

CAS: 18472-87-2

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Ion Channel Modulation||Product Type|Biochemicals|Labeling & Detection|Dyes, Stains, & Indicators||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|MRSA

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