A phenol with diverse biological activities; protects V79-4 Chinese hamster lung fibroblast cells from oxidative stress and inhibits lipid peroxidation by scavenging ROS; induces apoptosis in HT-29 human colon cancer cells; inhibits metastasis of BT549 and MDA-MB-231 human breast cancer cells; protects primary neurons from β-amyloid-induced dendritic spine loss; shortens the latency to find the platform in a Morris water maze test in an AD mouse model; used to stain histological plant sections and in the synthesis of numerous natural products; slows the frequency and decreases the amplitude of contraction in isolated rabbit and rat intestine at a concentration of 100 μM and 1 μM

Phloroglucinol – 100 g

Brand:
Cayman
CAS:
108-73-6
Storage:
4
UN-No:
Non-Hazardous - /

Phloroglucinol is a naturally occurring phenol that exhibits diverse biological activities.{39343} Phloroglucinol protects V79-4 Chinese hamster lung fibroblast cells from oxidative stress and inhibits lipid peroxidation by scavenging reactive oxygen species (ROS).{39345} It induces apoptosis in HT-29 human colon cancer cells and inhibits metastasis of BT549 and MDA-MB-231 human breast cancer cells.{39346,39347} Phloroglucinol protects primary neurons from β-amyloid-induced dendritic spine loss in vitro and shortens the latency to find the platform in a Morris water maze test in an Alzheimer’s disease (AD) mouse model.{39348} Phloroglucinol has been used to stain histological plant sections and in the synthesis of numerous natural products.{39349,39350,39353} Phloroglucinol slows the frequency and decreases the amplitude of contraction in isolated rabbit and rat intestine at a concentration of 100 and 1 μM, respectively.{39354} Formulations containing phloroglucinol have been used as antispasmodics.{39351,39352}  

 

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SKU: 23223 - 100 g Category:

Description

A phenol with diverse biological activities; protects V79-4 Chinese hamster lung fibroblast cells from oxidative stress and inhibits lipid peroxidation by scavenging ROS; induces apoptosis in HT-29 human colon cancer cells; inhibits metastasis of BT549 and MDA-MB-231 human breast cancer cells; protects primary neurons from β-amyloid-induced dendritic spine loss; shortens the latency to find the platform in a Morris water maze test in an AD mouse model; used to stain histological plant sections and in the synthesis of numerous natural products; slows the frequency and decreases the amplitude of contraction in isolated rabbit and rat intestine at a concentration of 100 μM and 1 μM, respectively

Formal name: 1,3,5-benzenetriol

Synonyms:  sym-Trihydroxybenzene|1,3,5-Hydroxybenzene|1,3,5-Trihydroxybenzene|Benzene-s-triol|NSC 1572

Molecular weight: 126.1

CAS: 108-73-6

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Labeling & Detection|Dyes, Stains, & Indicators||Product Type|Biochemicals|Natural Products||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Cancer|Cell Migration & Metastasis||Research Area|Neuroscience|Behavioral Neuroscience|Learning & Memory||Research Area|Neuroscience|Neurodegenerative Disorders|Alzheimer’s Disease||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Lipid Peroxidation||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen

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