A key intermediate in aerobic catabolism of phenylacetate in bacteria; a precursor in the synthesis of the antibiotic penicillin G; acts as an effector molecule

Phenylacetyl-Coenzyme A – 1 mg

Brand:
Cayman
CAS:
7532-39-0
Storage:
-20
UN-No:
Non-Hazardous - /

Phenylacetyl-coenzyme A (CoA) is a key intermediate in aerobic catabolism of phenylacetate in bacteria such as Pseudomonas, when cultured in minimal media using phenylacetate as the sole carbon source.{36237} It is a precursor in the synthesis of the antibiotic penicillin G (Item No. 21615) found in industrial strains of P. chrysogenum. Phenylacetyl-CoA also acts as an effector molecule of the TetR family transcriptional repressor PaaR in T. thermophilus and the GntR family transcriptional regulator PaaX in E. coli and Pseudomonas, binding to each protein to induce derepression of various genes.{36238}  

 

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SKU: 23550 - 1 mg Category:

Description

A key intermediate in aerobic catabolism of phenylacetate in bacteria; a precursor in the synthesis of the antibiotic penicillin G; acts as an effector molecule, binding to PaaR in T. thermophilus and PaaX in E. coli and Pseudomonas to induce derepression of various genes

Formal name: S-(benzeneacetate) coenzyme A

Synonyms:  Phenylacetyl-CoA

Molecular weight: 885.7

CAS: 7532-39-0

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Microbial Metabolites||Research Area|Endocrinology & Metabolism|Cofactors & Vitamins||Research Area|Immunology & Inflammation

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