An AChE inhibitor (IC50 = 24 nM) that prevents amyloid-β production by diminishing the expression of APP

Phenserine – 5 mg

Brand:
Cayman
CAS:
101246-66-6
Storage:
-20
UN-No:
Non-Hazardous - /

Phenserine is an analog of physostigmine that inhibits acetylcholinesterase with an IC50 value of 24 nM.{24084,24085} It is reported to prevent amyloid-β production by diminishing the expression of amyloid-β precursor protein.{33006}  

 

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Description

An AChE inhibitor (IC50 = 24 nM) that prevents amyloid-β production by diminishing the expression of APP

Formal name: (3aS,8aR)-5-(N-phenylcarbamate)1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethyl-pyrrolo[2,3-b]indol-5-ol

Synonyms:  (-)-Eseroline phenylcarbamate|(-)-N-Phenylcarbamoyleseroline|(-)-Phenserine

Molecular weight: 337.4

CAS: 101246-66-6

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|Acetylcholine Turnover||Research Area|Neuroscience|Neurodegenerative Disorders|Alzheimer’s Disease

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