Description
An inhibitor of MAO (IC50 = 0.9 μM using rat brain mitochondrial preparations); potentiates the effects of tryptamine on isolated rat fundus (EC50 = 90 nM) and increases tryptamine toxicity in mice (LD50s = 85 and 500 mg/kg in the presence and absence of phenelzine, respectively); increases GABA, dopamine, 5-HT, and norepinephrine levels in the hippocampus and cortex of socially isolated rats and rats treated with the NMDA receptor antagonist (+)-MK-801 when administered at a dose of 20 mg/kg; increases 5-HT levels in the ventral horn of the spinal cord, improves gross motor ability in a rotarod test, and increases locomotor activity in an open field test in mice with experimental autoimmune encephalomyelitis when administered at a dose of 30 mg/kg,
Formal name: (2-phenylethyl)-hydrazine, monosulfate
Synonyms: NSC 170957|W-1544A
Molecular weight: 234.3
CAS: 156-51-4
Purity: ≥98%
Formulation: A solid
Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Neuroscience|Behavioral Neuroscience