An antibiotic; active against β-hemolytic Streptoccus

Phenelfamycin E – 5 mg

Brand:
Cayman
CAS:
114451-31-9
Storage:
-20
UN-No:
Non-Hazardous - /

Phenelfamycin E is an antibiotic originally isolated from Streptomyces.{43960} It is active against β-hemolytic Streptoccus, S. pneumoniae, C. difficile, C. perfringens, and P. magnus Gram-positive bacteria (MICs = 0.12-1, 0.25-2, 4, 16, and 0.12 μg/ml, respectively) but not a panel of seven Gram-negative bacteria (MICs = >128 μg/ml).{43961} Phenelfamycin E (4-64 mg/kg) increases survival in a mouse model of lethal S. pyogenes infection in a dose-dependent manner. Dietary administration of phenelfamycin E increases body weight in chickens.  

 

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SKU: 28168 - 5 mg Category:

Description

An antibiotic; active against β-hemolytic Streptoccus, S. pneumoniae, C. difficile, C. perfringens, and P. magnus Gram-positive bacteria (MICs = 0.12-1, 0.25-2, 4, 16, and 0.12 μg/ml, respectively); increases survival in a mouse model of lethal S. pyogenes infection from 4-64 mg/kg; increases body weight in chickens

Formal name: benzeneacetic acid, (2R,3R,4R,6S)-2-[(1S)-2-[[(2E,4E,6S,7S)-7-[(2R,4S,5S)-5-[(1E,3E,5E)-6-carboxy-1,3,5-hexatrienyl]tetrahydro-4-hydroxy-2-furanyl]-6-methoxy-5-methyl-2,4-octadienyl]amino]-1-[[[O-2,6-dideoxy-3-O-methyl-α-L-lyxo-hexopyranosyl-(1→4)-(O-2,6-dideoxy-3-O-methyl-β-L-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-3-O-methyl-α-L-lyxo-hexopyranosyl]oxy]methyl]-2-oxoethyl]tetrahydro-2,4-dihydroxy-5,5-dimethyl-6-[(1E,3Z)-1,3-pentadienyl]-2H-pyran-3-yl ester

Synonyms:  Ganefromycin α

Molecular weight: 1,226.40

CAS: 114451-31-9

Purity: ≥95%

Formulation: A solid

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