A free radical generator; has been used as an electron transfer reactant in cell viability assays; induces ssDNA break formation in the presence of NADPH in a cell-free plasmid cleavage assay; induces oxidative DNA damage in an alkaline comet assay and apoptosis in A375 melanoma cells at 10 µM; oxidizes cysteine-containing proteins in HepG2 cells at 20 nM

Phenazine (methosulfate) – 5 g

Brand:
Cayman
CAS:
299-11-6
Storage:
-20
UN-No:
Non-Hazardous - /

Phenazine is a free radical generator.{56020} It has been used as an electron transfer reactant in cell viability assays.{56021} Phenazine (10 µM) induces ssDNA break formation in the presence of the reducing agent NADPH in a cell-free plasmid cleavage assay when used at a concentration of 10 µM. It induces oxidative DNA damage in an alkaline comet assay and apoptosis in A375 melanoma cells when used at a concentration of 10 µM. Phenazine (20 nM) oxidizes cysteine-containing proteins in HepG2 cells.{56020}  

 

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SKU: 30558 - 5 g Category:

Description

A free radical generator; has been used as an electron transfer reactant in cell viability assays; induces ssDNA break formation in the presence of NADPH in a cell-free plasmid cleavage assay; induces oxidative DNA damage in an alkaline comet assay and apoptosis in A375 melanoma cells at 10 µM; oxidizes cysteine-containing proteins in HepG2 cells at 20 nM

Formal name: 5-methyl-phenazinium, methyl sulfate

Synonyms:  NSC 34661

Molecular weight: 306.3

CAS: 299-11-6

Purity: ≥98%

Formulation: A crystalline solid

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